kallmann syndrome and deafness: an uncommon combination: a case report and a literature review

background: kallmann syndrome (kal s) is an isolated form of hypogonadotrophic hypogonadism in combination with a defect in smell sensation. depending on the genetic form of the disease, a number of non-reproductive, non-olfactory abnormalities may also be existent. in the present report, we describe a male with kal s associated with hearing loss, and the successful treatment of his sexual and reproductive defects. case: a 23-year-old caucasian man presented with a lifelong lack of erection and ejaculation. the patient reported also anosmia combined with loss of hearing ability. a diagnostic work-up identified the presence of kal s associated with sensorineural hearing loss. administration of gonadotrophins regained the erection and a viable-sperm containing ejaculation. conclusion: lack of erection and ejaculation are important components of delayed puberty which could lead to diagnosis of kal s. the existence of a hearing impairment in the reported patient makes the recommendation to screen the hearing ability in kal s of utmost importance.